Original article
Developments and Quality Assurance in Stem Cell Transplantation – Data from a German National Registry
Dtsch Arztebl 2006; 103(37): A-2381
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Introduction: The Deutsches Register für Stammzelltransplantationen e.V. (DRST) collects unique data on all hematopoietic stem cell transplantations (HSCT) in Germany from 1998 onwards, in close cooperation with all German centers for HSCT. Methods: Analysis of DRST data. Results: Peripheral blood stem cells (PBSCT) are now the preferred stem cell source over bone marrow. Since 1998 the number of allogeneic stemcell transplantations in Germany has increased steadily. In 2001 for the first time the majority of allogeneic HSCT in Germany were sourced from unrelated donors. After a transient decrease, the number of autologous HSCT has been rising again since 2002, reflecting in particular transplants performed for multiple myeloma and Non-Hodgkins-Lymphoma. The number of autologous SCT for solid tumours, on the other hand, which was transiently one of the main indications for autologous SCT in the 1990s, has now dropped considerably. Discussion: The DRST has successfully established itself as the National Registry for HSCT in Germany. It provides the basis for quality assurance measures and serves as a platform for scientific studies with the aim of further improvement of HSCT. Dtsch Arztebl 2006; 103(37): A 2381–6. Key words: hematopoietic stem cell transplantation, hematopoietic stem cells, stem cell donors, national registry, quality assurance
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