DÄ internationalArchive24/2015Repetitive Transcranial Magnetic Stimulation
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We think that this review (1) is in actual fact very relevant, but somewhat incomplete as it does not include repetitive transcranial magnetic stimulation (rTMS) as a treatment option. This method, though not approved in Germany, has been cleared for use in the United States and several European and non-European countries. In Germany, rTMS may be used within the legal framework of an individual treatment attempt (compassionate use). Scientific evidence of its efficacy in chronic and treatment-resistant depression is available, showing both statistically significant and clinically relevant benefits (2) and recently it has been recommended in the guidelines on the therapeutic use of repetitive transcranial magnetic stimulation with a high (A) level of evidence (3).

DOI: 10.3238/arztebl.2015.0421a

Dr. med. Stephan. G. Zipper

St. Marien-Krankenhaus Frankfurt/Main,
Frankfurt/Main
zipper@em.uni-frankfurt.de

Conflict of interest statement
The author declares that no conflict of interest exists.

1.
Bschor T, Bauer M, Adli M: Chronic and treatment resistant depression—diagnosis and stepwise therapy. Dtsch Arztebl Int 2014; 111: 766–76 VOLLTEXT
2.
George MS, Lisanby SH, Avery D, et al.: Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder a sham-controlled randomized trial. Arch Gen Psychiatry 2010 ;67: 507–16 CrossRef MEDLINE
3.
Lefaucheur JP, André-Obadia N, Antal A, et al.: Guidelines. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clin Neurophysiol 2014; 125: 2150–206 CrossRef MEDLINE
1.Bschor T, Bauer M, Adli M: Chronic and treatment resistant depression—diagnosis and stepwise therapy. Dtsch Arztebl Int 2014; 111: 766–76 VOLLTEXT
2.George MS, Lisanby SH, Avery D, et al.: Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder a sham-controlled randomized trial. Arch Gen Psychiatry 2010 ;67: 507–16 CrossRef MEDLINE
3.Lefaucheur JP, André-Obadia N, Antal A, et al.: Guidelines. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clin Neurophysiol 2014; 125: 2150–206 CrossRef MEDLINE

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