DÄ internationalArchive18/2020Coronary stent thrombosis—predictors and prevention

Review article

Coronary stent thrombosis—predictors and prevention

Dtsch Arztebl Int 2020; 117: 320-6. DOI: 10.3238/arztebl.2020.0320

Ullrich, H; Münzel, T; Gori, T

For technical reasons, the English full text will be published approximately two weeks after the German print edition has been published.

Zentrum für Kardiologie, Kardiologie 1, Universitätsmedizin Mainz,
Deutsches Zentrum für Herz- und Kreislaufforschung, Standort Rhein-Main:
Helen Ullrich, Prof. Dr. med. Thomas Münzel, Prof. Dr. Tommaso Gori
1.Claessen BE, Henriques JP, Jaffer FA, Mehran R, Piek JJ, Dangas GD: Stent thrombosis: a clinical perspective. JACC Cardiovasc Interv 2014; 7: 1081–92 CrossRef MEDLINE
2.Iakovou I, Schmidt T, Bonizzoni E, et al.: Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA 2005; 293: 2126–30 CrossRef MEDLINE
3.Lemesle G, Tricot O, Meurice T, et al.: Incident myocardial infarction and very late stent thrombosis in outpatients with stable coronary artery disease. J Am Coll Cardiol 2017; 69: 2149–56 CrossRef MEDLINE
4.Cutlip DE, Windecker S, Mehran R, et al.: Clinical end points in coronary stent trials: a case for standardized definitions. Circulation 2007; 115: 2344–51 CrossRef MEDLINE
5.D‘Ascenzo F, Bollati M, Clementi F, et al.: Incidence and predictors of coronary stent thrombosis: evidence from an international collaborative meta-analysis including 30 studies, 221,066 patients, and 4276 thromboses. Int J Cardiol 2013; 167: 575–84 CrossRef MEDLINE
6.Cuculi F, Puricel S, Jamshidi P, et al.: Optical coherence tomography findings in bioresorbable vascular scaffolds thrombosis. Circ Cardiovasc Interv 2015; 8: e002518 CrossRef MEDLINE
7.Byrne RA, Joner M, Kastrati A: Stent thrombosis and restenosis: what have we learned and where are we going? The Andreas Grüntzig Lecture ESC 2014. Eur Heart J 2015; 36: 3320–31 CrossRef MEDLINE PubMed Central
8.Schömig A, Neumann FJ, Kastrati A, et al.: A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med 1996; 334: 1084–9 CrossRef MEDLINE
9.Leon MB, Baim DS, Popma JJ, et al.: A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent anticoagulation restenosis study investigators. N Engl J Med 1998; 339: 1665–71 CrossRef MEDLINE
10.Kedhi E, Joesoef KS, McFadden E, et al.: Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial. Lancet 2010; 375: 201–9 CrossRef MEDLINE
11.Ali ZA, Gao R, Kimura T, et al.: Three-year outcomes with the absorb bioresorbable scaffold: individual-patient-data meta-analysis from the ABSORB randomized trials. Circulation 2018; 137: 464–79 CrossRef MEDLINE
12.Polimeni A, Anadol R, Münzel T, Indolfi C, De Rosa S, Gori T: Long-term outcome of bioresorbable vascular scaffolds for the treatment of coronary artery disease: a meta-analysis of RCTs. BMC Cardiovasc Disord 2017; 17: 147 MEDLINE MEDLINE PubMed Central
13.Schulz S, Schuster T, Mehilli J, et al.: Stent thrombosis after drug-eluting stent implantation: incidence, timing, and relation to discontinuation of clopidogrel therapy over a 4-year period. Eur Heart J 2009; 30: 2714–21 CrossRef MEDLINE
14. Knuuti J, Wijns W, Saraste A, et al.: 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J 2019; 00: 1–71. doi:10.1093/eurheartj/ehz425 CrossRef MEDLINE
15.Valgimigli M, Bueno H, Byrne RA, et al.: 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: The Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J 2018; 39: 213–60 CrossRef MEDLINE
16.Varenne O, Cook S, Sideris G, et al.: Drug-eluting stents in elderly patients with coronary artery disease (SENIOR): a randomised single-blind trial. Lancet 2018; 391: 41–50 CrossRef MEDLINE
17.Valgimigli M, Borghesi M, Tebaldi M, et al.: Should duration of dual antiplatelet therapy depend on the type and/or potency of implanted stent? A pre-specified analysis from the PROlonging Dual antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY (PRODIGY). Eur Heart J 2013; 34: 909–19 CrossRef MEDLINE
18.Yeh RW, Kereiakes DJ, Steg PG, et al.: Lesion complexity and outcomes of extended dual antiplatelet therapy after percutaneous coronary intervention. J Am Coll Cardiol 2017; 70: 2213–23 CrossRef MEDLINE
19.Verdoia M, Kedhi E, Ceccon C, Suryapranata H, De Luca G: Duration of dual antiplatelet therapy and outcome in patients with acute coronary syndrome undergoing percutaneous revascularization: a meta-analysis of 11 randomized trials. Int J Cardiol 2018; 264: 30–8 CrossRef MEDLINE
20.Valgimigli M, Bueno H, Byrne RA, et al.: 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS - Web Addenda. https://academic.oup.com/DocumentLibrary/EHJ/SupplementaryData/ehx419web.pdf (last accessed on 2 April 2020).
21.Costa F, van Klaveren D, James S, et al.: Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials. Lancet 2017; 389: 1025–34 CrossRef MEDLINE
22.Généreux P, Rutledge DR, Palmerini T, et al.: Stent thrombosis and dual antiplatelet therapy interruption with everolimus-eluting stents: insights from the Xience V Coronary Stent System trials. Circ Cardiovasc Interv 2015; 8: pii: e001362 CrossRef
23.van Werkum JW, Heestermans AA, Zomer AC, et al.: Predictors of coronary stent thrombosis: the Dutch Stent Thrombosis Registry. J Am Coll Cardiol 2009; 53: 1399–409 CrossRef MEDLINE
24.Camenzind E, Steg PG, Wijns W: Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern. Circulation 2007; 115: 1440–55 CrossRef MEDLINE
25.McFadden EP, Stabile E, Regar E, et al.: Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy. Lancet 2004; 364: 1519–21 CrossRef MEDLINE
26.Palmerini T, Biondi-Zoccai G, Della Riva D, et al.: Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis. Lancet 2012; 379: 1393–402 CrossRef MEDLINE
27.Jensen LO, Thayssen P, Maeng M, et al.: Randomized comparison of a biodegradable polymer ultrathin strut sirolimus-eluting stent with a biodegradable polymer biolimus-eluting stent in patients treated with percutaneous coronary intervention: The SORT OUT VII Trial. Circ Cardiovasc Interv 2016; 9: pii: e003610 CrossRef
28.Neumann FJ, Sousa-Uva M, Ahlsson A, et al.: 2018 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J 2019; 40: 87–165 CrossRef CrossRef
29.Buccheri S, Franchina G, Romano S, et al.: Clinical outcomes following intravascular imaging-guided versus coronary angiography-guided percutaneous coronary intervention with stent implantation: a systematic review and bayesian network meta-analysis of 31 studies and 17,882 patients. JACC Cardiovasc Interv 2017; 10: 2488–98 CrossRef MEDLINE
30.Maehara A, Matsumura M, Ali ZA, Mintz GS, Stone GW: IVUS-guided versus OCT-guided coronary stent implantation: a critical appraisal. JACC Cardiovasc Imaging 2017; 10: 1487–503 CrossRef MEDLINE
31.Souteyrand G, Amabile N, Mangin L, et al.: Mechanisms of stent thrombosis analysed by optical coherence tomography: insights from the national PESTO French registry. Eur Heart J 2016; 37: 1208–16 CrossRef MEDLINE
32.Sethi A, Singbal Y, Rastogi U, Prasad VS: Late incomplete stent apposition is associated with late/very late stent thrombosis: a meta-analysis. Catheter Cardiovasc Interv 2018; 91: 365–75 CrossRef MEDLINE
33.Jang JS, Song YJ, Kang W, et al.: Intravascular ultrasound-guided implantation of drug-eluting stents to improve outcome: a meta-analysis. JACC Cardiovasc Interv 2014; 7: 233–43 CrossRef MEDLINE
34.Prati F, Romagnoli E, La Manna A, et al.: Long-term consequences of optical coherence tomography findings during percutaneous coronary intervention: the Centro Per La Lotta Contro L‘infarto-Optimization Of Percutaneous Coronary Intervention (CLI-OPCI) LATE study. EuroIntervention 2018; 14: e443–51 CrossRef MEDLINE
35.Kubo T, Shinke T, Okamura T, et al.: Optical frequency domain imaging vs. intravascular ultrasound in percutaneous coronary intervention (OPINION trial): one-year angiographic and clinical results. Eur Heart J 2017; 38: 3139–47 CrossRef MEDLINE PubMed Central
36.Ali ZA, Maehara A, Généreux P, et al.: Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial. Lancet 2016; 388: 2618–28 CrossRef MEDLINE
37.Pasceri V, Pelliccia F, Pristipino C, et al.: Clinical effects of routine postdilatation of drug-eluting stents. Catheter Cardiovasc Interv 2014; 83: 898–904 CrossRef MEDLINE
38.Serruys PW, Kogame N, Katagiri Y, et al.: Clinical outcomes of state-of-the-art percutaneous coronary revascularisation in patients with three-vessel disease: two-year follow-up of the SYNTAX II study. EuroIntervention 2019; 15: e244–52 CrossRef MEDLINE
39.Dangas GD, Claessen BE, Mehran R, et al.: Development and validation of a stent thrombosis risk score in patients with acute coronary syndromes. JACC Cardiovasc Interv 2012; 5: 1097–105 CrossRef MEDLINE
40.Räber L, Mintz GS, Koskinas KC, et al.: Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions. Eur Heart J 2018; 39: 3281–300 CrossRef MEDLINE
e1. MedMarket Diligence, LLC: Global dynamics of surgical and interventional cardiovascular procedures, 2015–2022. (Report #C500). MedMarket Diligence 2016.
e2.Iqbal J, Sumaya W, Tatman V, et al.: Incidence and predictors of stent thrombosis: a single-centre study of 5,833 consecutive patients undergoing coronary artery stenting. EuroIntervention 2013; 9: 62–9 CrossRef MEDLINE
e3.Amabile N, Trouillet C, Meneveau N, et al.: Mechanical abnormalities associated with first- and second-generation drug-eluting stent thrombosis analyzed by optical coherence tomography in the national PESTO French registry. Int J Cardiol 2017; 227: 161–5 CrossRef MEDLINE
e4.Sigwart U, Puel J, Mirkovitch V, Joffre F, Kappenberger L: Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N Engl J Med 1987; 316: 701–6 CrossRef MEDLINE
e5.Garg S, Serruys PW: Coronary stents: current status. J Am Coll Cardiol 2010; 56: S1–42 CrossRef MEDLINE
e6.Chen KY, Rha SW, Li YJ, et al.: Comparisons of everolimus and paclitaxel-eluting stents in patients with acute myocardial infarction. J Interv Cardiol 2015; 28: 147–56 CrossRef MEDLINE
e7.Stefanini GG, Taniwaki M, Windecker S: Coronary stents: novel developments. Heart 2014; 100: 1051–61 CrossRef MEDLINE
e8.Yin Y, Zhang Y, Zhao X: Safety and efficacy of biodegradable drug-eluting vs. bare metal stents: a meta-analysis from randomized trials. PLoS One 2014; 9: e99648 CrossRef MEDLINE PubMed Central
e9.Haude M, Ince H, Abizaid A, et al.: Sustained safety and performance of the second-generation drug-eluting absorbable metal scaffold in patients with de novo coronary lesions: 12-month clinical results and angiographic findings of the BIOSOLVE-II first-in-man trial. Eur Heart J 2016; 37: 2701–9 CrossRef MEDLINE PubMed Central
e10.Bansilal S, Bonaca MP, Cornel JH, et al.: Ticagrelor for secondary prevention of atherothrombotic events in patients with multivessel coronary disease. J Am Coll Cardiol 2018; 71: 489–96 CrossRef MEDLINE
e11.Deutsche Gesellschaft für Kardiologie – Herz-und Kreislaufforschung e.V.: ESC pocket guidelines. Duale antithrombozytäre Therapie (DAPT) bei Koronarer Herzkrankheit. Version 2017. Gründwald: Börm Bruckmeier Verlag GmbH 2018.
e12.Poon EKW, Thondapu V, Hayat U, et al.: Elevated blood viscosity and microrecirculation resulting from coronary stent malapposition. J Biomech Eng 2018; 140: doi: 10.1115/1.4039306 CrossRef MEDLINE
e13.Yamashita T, Sakamoto K, Tabata N, et al.: Imaging-guided PCI for event suppression in Japanese acute coronary syndrome patients: community based observational cohort registry. Cardiovasc Interv Ther 2020. doi: 10.1007/s12928–020–00649–3. [Epub ahead of print] CrossRef