DÄ internationalArchive20/2008Salicylate Intolerance – Pathophysiology, Clinical Spectrum, Diagnosis and Therapy: In Reply

Correspondence

Salicylate Intolerance – Pathophysiology, Clinical Spectrum, Diagnosis and Therapy: In Reply

Dtsch Arztebl Int 2008; 105(20): 384. DOI: 10.3238/arztebl.2008.0384b

Baenkler, H

LNSLNS Professor Stichtenoth's comments are correct; they should be generally accepted. Thus, the widely used term "analgesic intolerance" is wrong. It is particularly important in medicine to use precise definitions, as medicine is often felt to be an art rather than a science.

This is unfortunately not always successful enough during routine work. There are always "exceptional cases", which is why (as pointed out by Professor Stichtenoth) the contraindication is still included as a precaution in the summaries of product characteristics for the coxibs.

As my article was intended to be an overview of the arachidonic acideicosanoid complex, and not just to cover intolerance, I should just add that the special features I described also include proliferation, especially in the gastrointestinal tract. DOI: 10.3238/arztebl.2008.0384b

Prof. Dr. med. Hanns-Wolf Baenkler
Medizinische Universitätsklinik 3
Krankenhausstr. 12
91054 Erlangen, Germany

Conflict of interest statement
The author holds the patent for the functional eicosanoid test.

Translated from the original German by Rodney A. Yeates, M.A., Ph.D.