DÄ internationalArchiveReferences
References

cme

Cancer-Related Fatigue

Dtsch Arztebl Int 2012; 109(9): 161-72; DOI: 10.3238/arztebl.2012.0161

Horneber, M; Fischer, I; Dimeo, F; Rüffer, J U; Weis, J

1. Weis J: Cancer-related fatigue: prevalence, assessment and treatment strategies. Expert Rev Pharmacoecon Outcomes Res 2011; 11: 441–6. CrossRef MEDLINE
2. Berger AM, Abernethy AP, Atkinson A, et al.: Cancer-related
fatigue. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines TM) Version 1.2011
3. Donner-Banzhoff N, Maisel P, Dörr C, Baum E: Müdigkeit –
DEGAM Leitlinie Nr. 2. AWMF Register Nr.053/002. Stand 2006. Göttingen, Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM).
4. Radbruch L, Strasser F, Elsner F, et al.: Fatigue in palliative care patients – an EAPC approach. Palliat Med 2008; 22: 13–32. CrossRef MEDLINE
5. Scott JA, Lasch KE, Barsevick AM, Piault-Louis E: Patients’
experiences with cancer-related fatigue: a review and synthesis of qualitative research. Oncol Nurs Forum 2011; 38: 191–203.
6. Piper BF, Cella D: Cancer-related fatigue: definitions and clinical subtypes. J Natl Compr Canc Netw 2010; 8: 958–66. MEDLINE
7. Ancoli-Israel S, Moore PJ, Jones V: The relationship between
fatigue and sleep in cancer patients: a review. Eur J Cancer Care 2001; 10: 245–55. CrossRef MEDLINE PubMed Central
8. Brown LF, Kroenke K: Cancer-related fatigue and its associations with depression and anxiety: a systematic review. Psychosomatics 2009; 50: 440–7. MEDLINE PubMed Central
9. Rüffer JU, Flechtner H, Tralls P, Josting A, Sieber M, Lathan B, et al.: Fatigue in long-term survivors of Hodgkin’s lymphoma; a
report from the German Hodgkin Lymphoma Study Group (GHSG). Eur J Cancer 2003; 39: 2179–86. CrossRef MEDLINE
10. Cheng KK, Lee DT: Effects of pain, fatigue, insomnia, and
mood disturbance on functional status and quality of life of
elderly patients with cancer. Crit Rev Oncol Hematol 2011; 78: 127–37. CrossRef MEDLINE
11. Vogelzang NJ, Breitbart W, Cella D, et al.: Patient, caregiver, and oncologist perceptions of cancer-related fatigue. Results of a tripart assessment survey. Semin Hematol 1997; 34: 4–12. MEDLINE
12. Newell S, Sanson-Fisher RW, Girgis A, Bonaventura A: How well do medical oncologists’ perceptions reflect their patients’ reported physical and psychosocial problems? Data from a survey of five oncologists. Cancer 1998; 83: 1640–51. CrossRef MEDLINE
13. Singer S, Kuhnt S, Zwerenz R, et al.: Age- and sex-standardised prevalence rates of fatigue in a large hospital-based sample of cancer patients. Br J Cancer 2011; 105: 445–51. CrossRef MEDLINE
14. Bruera E: Cancer-related fatigue: a multidimensional syndrome. J Support Oncol 2010; 8: 175–6. MEDLINE
15. Barsevick A, Frost M, Zwinderman A, Hall P, Halyard M: I’m so tired: biological and genetic mechanisms of cancer-related fatigue. Qual Life Res 2010; 19: 1419–27. CrossRef CrossRef PubMed Central
16. Kangas M, Bovbjerg DH, Montgomery GH: Cancer-related fatigue: a systematic and meta-analytic review of non-pharmacological therapies for cancer patients. Psychol Bull 2008; 134: 700–41. CrossRef MEDLINE
17. Goedendorp MM, Gielissen MF, Verhagen CA, Bleijenberg G: Psychosocial interventions for reducing fatigue during cancer treatment in adults. Cochrane Database Syst Rev 2009; CD006953. MEDLINE
18.Dimeo FC: Effects of exercise on cancer-related fatigue. Cancer 2001; 92: 1689–93. CrossRef MEDLINE
19. Deutsche Krebsgesellschaft: Richtlinien für die Anwendung von Sport und körperlicher Aktivität in der Prävention, supportiver Therapie und Rehabilitation neoplastischer Erkrankungen Teil II. FORUM 2011; 5: 9–12.
20. Dimeo F: Standards in der Sportmedizin: Körperliche Aktivität und Krebs. Zeitschrift für Sportmedizin 2004; 4: 106–7.
21. McNeely ML, Courneya KS: Exercise programs for cancer-related fatigue: evidence and clinical guidelines. J Natl Compr Canc Netw 2010; 8: 945–53. MEDLINE
22. Baumann FT: Ausdauertraining mit Krebspatienten. In: Baumann FT, Schüle K, (eds.): Bewegungstherapie und Sport bei Krebs. Leitfaden für die Praxis. Köln: Deutscher Ärzte-Verlag GmbH; 2008: 33–55.
23. Breitbart W, Alici Y: Psychostimulants for cancer-related fatigue. J Natl Compr Canc Netw 2010; 8: 933–42. MEDLINE
24. Minton O, Richardson A, Sharpe M, Hotopf M, Stone PC:
Psychostimulants for the management of cancer-related fatigue: A systematic review and meta-analysis. J Pain Symptom Manage 2011; 41: 761–7. CrossRef MEDLINE
25. Cooper MR, Bird HM, Steinberg M: Efficacy and safety of
modafinil in the treatment of cancer-related fatigue. Ann
Pharmacother 2009; 43: 721–5. CrossRef MEDLINE
e1. Holley S: Cancer-related fatigue. Suffering a different fatigue. Cancer Pract 2000; 8: 87–95. CrossRef MEDLINE
e2. Tishelman C, Degner LF, Rudman A, et al.: Symptoms in patients with lung carcinoma: distinguishing distress from intensity. Cancer 2005; 104: 2013–21. MEDLINE
e3. Shi Q, Smith TG, Michonski JD, Stein KD, Kaw C, Cleeland CS: Symptom burden in cancer survivors 1 year after diagnosis: A Report from the american cancer society’s studies of cancer survivors. Cancer 2011; 117: 2779–90. MEDLINE
e4. Scott JA, Lasch KE, Barsevick AM, Piault-Louis E: Patients’ experiences with cancer-related fatigue: a review and synthesis of qualitative research. Oncol Nurs Forum 2011; 38: E191–E203. CrossRef MEDLINE
e5. Gotay CC, Kawamoto CT, Bottomley A, Efficace F: The prognostic significance of patient-reported outcomes in cancer clinical trials. J Clin Oncol 2008; 26: 1355–63. CrossRef MEDLINE
e6. Montazeri A: Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008. Health Qual Life Outcomes 2009; 7: 102. CrossRef MEDLINE PubMed Central
e7. Servaes P, Gielissen MF, Verhagen S, Bleijenberg G: The course of severe fatigue in disease-free breast cancer patients: a longitudinal study. Psychooncology 2007; 16: 787–95. CrossRef MEDLINE
e8. Kuhnt S, Ehrensperger C, Singer S, et al.: Prädiktoren tumorassoziierter Fatigue. Psychotherapeut 2011; 56: 216–23.
e9.Smith SK, Herndon JE, Lyerly HK, et al.: Correlates of quality of life-related outcomes in breast cancer patients participating in the Pathfinders pilot study. Psychooncology 2011; 20: 559–64. MEDLINE
e10. Spelten ER, Sprangers MA, Verbeek JH: Factors reported to influence the return to work of cancer survivors: a literature review. Psychooncology 2002; 11: 124–31. CrossRef MEDLINE
e11. Tiedtke C, de Rijk A, Dierckx de Casterlé B, Christiaens MR, Donceel P: Experiences and concerns about ’returning to work’ for women breast cancer survivors: a literature review. Psychooncology 2010; 19: 677–83. MEDLINE
e12. Oktay JS, Bellin MH, Scarvalone S, Appling S, Helzlsouer KJ: Managing the impact of posttreatment fatigue on the family: Breast cancer survivors share their experiences. Fam Syst Health 2011; 29: 127–37. CrossRef MEDLINE
e13. Shun SC, Lai YH, Hsiao FH: Patient-related barriers to fatigue communication in cancer patients receiving active treatment. Oncologist 2009; 14: 936–43. CrossRef MEDLINE
e14. Westerman MJ, The AM, Sprangers MA, Groen HJ, van der Wal G, Hak T: Small-cell lung cancer patients are just ’a little bit’ tired: response shift and self-presentation in the measurement of fatigue. Qual Life Res 2007; 16: 853–61. CrossRef MEDLINE PubMed Central
e15. Pearce S, Richardson A: Fatigue in cancer: a phenomenological perspective. Eur J Cancer Care 1996; 5: 111–5. CrossRef MEDLINE
e16.Passik SD, Kirsh KL, Donaghy K, et al.: Patient-related barriers to fatigue communication: initial validation of the fatigue management barriers questionnaire. J Pain Symptom Manage 2002; 24: 481–93. MEDLINE
e17. Smets EM, Garssen B, Bonke B, de Haes JC: The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res 1995; 39: 315–25. CrossRef MEDLINE
e18. Kuhnt S, Ernst J, Singer S, et al.: Fatigue in cancer survivors—prevalence and correlates. Onkologie 2009; 32: 312–7.
e19. Schultz SL, Dalton SO, Christensen J, Carlsen K, Ross L, Johansen C: Factors correlated with fatigue in breast cancer survivors undergoing a rehabilitation course, Denmark, 2002–2005. Psychooncology 2010; 20: 352–60. MEDLINE
e20. Cella D, Davis K, Breitbart W, Curt G: Cancer-related fatigue: prevalence of proposed diagnostic criteria in a United States sample of cancer survivors. J Clin Oncol 2001; 19: 3385–91. MEDLINE
e21. Knobel H, Havard LJ, Brit LM, Forfang K, Nome O, Kaasa S: Late medical complications and fatigue in Hodgkin’s disease survivors. J Clin Oncol 2001; 19: 3226–33. MEDLINE
e22. Bower JE, Ganz PA, Irwin MR, Kwan L, Breen EC, Cole SW: Inflammation and behavioral symptoms after breast cancer treatment: do fatigue, depression, and sleep disturbance share a common underlying mechanism? J Clin Oncol 2011; 29: 3517–22. CrossRef MEDLINE
e23. Bower JE, Ganz PA, Aziz N, Olmstead R, Irwin MR, Cole SW: Inflammatory responses to psychological stress in fatigued breast cancer survivors: relationship to glucocorticoids. Brain Behav Immun 2007; 21: 251–8. MEDLINE
e24.Schubert C, Hong S, Natarajan L, Mills PJ, Dimsdale JE: The association between fatigue and inflammatory marker levels in cancer patients: a quantitative review. Brain Behav Immun 2007; 21: 413–27. MEDLINE
e25. Jager A, Sleijfer S, van der Rijt CC: The pathogenesis of cancer related fatigue: could increased activity of pro-inflammatory cytokines be the common denominator? Eur J Cancer 2008; 44: 175–81. CrossRef MEDLINE
e26. Kamath J, Yarbrough GG, Prange AJ Jr., Winokur A: The thyrotropin-releasing hormone (TRH)-immune system homeostatic hypothesis. Pharmacol Ther 2009; 121: 20–8. MEDLINE
e27.Kamath J, Yarbrough GG, Prange AJ Jr., Winokur A: Thyrotropin-releasing hormone can relieve cancer-related fatigue: hypothesis and preliminary observations. J Int Med Res 2009; 37: 1152–7. MEDLINE
e28. Strasser F, Palmer JL, Schover LR, et al.: The impact of hypogonadism and autonomic dysfunction on fatigue, emotional function, and sexual desire in male patients with advanced cancer: a pilot study. Cancer 2006; 107: 2949–57. MEDLINE
e29. Bower JE: Cancer-related fatigue: links with inflammation in cancer patients and survivors. Brain Behav Immun 2007; 21: 863–71. CrossRef MEDLINE
e30. Alexander S, Stone P, White S, Andrews P, Nussey S, Bano G: Evaluation of central serotonin sensitivity in breast cancer survivors with cancer-related fatigue syndrome. J Pain Symptom Manage 2010; 40: 892–8. MEDLINE
e31. Payne, JK: Altered Circadian Rhythms and Cancer-Related Fatigue Outcomes. Integr Cancer Ther 2011; 10(3): 221–233 doi: 10.1177/1534735410392581. Epub 2011 Mar 7 CrossRef MEDLINE
e32. Berger AM, Wielgus K, Hertzog M, Fischer P, Farr L: Patterns of circadian activity rhythms and their relationships with fatigue and anxiety/depression in women treated with breast cancer adjuvant chemotherapy. Support Care Cancer 2009; 18: 114. MEDLINE
e33. Rich TA: Symptom clusters in cancer patients and their relation to EGFR ligand modulation of the circadian axis. J Support Oncol 2007; 5: 167–74. MEDLINE
e34. Sprangers MA, Bartels M, Veenhoven R, et al.: Which patient will feel down, which will be happy? The need to study the genetic disposition of emotional states. Qual Life Res 2010; 19: 1429–37. MEDLINE
e35.Whistler T, Taylor R, Craddock RC, Broderick G, Klimas N, Unger ER: Gene expression correlates of unexplained fatigue. Pharmacogenomics 2006; 7: 395–405. MEDLINE
e36. Reinertsen KV, Grenaker Alnaes GI, Landmark-Hoyvik H, et al.:
Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway. Brain Behav Immun 2011; 25: 1376–83. CrossRef MEDLINE
e37. Bower JE, Ganz PA, Irwin MR, Arevalo JM, Cole SW: Fatigue and gene expression in human leukocytes: increased NF-kappaB and decreased glucocorticoid signaling in breast cancer survivors with persistent fatigue. Brain Behav Immun 2011; 25: 147–50. MEDLINE
e38. Yavuzsen T, Davis MP, Ranganathan VK, et al.: Cancer-related fatigue: central or peripheral? J Pain Symptom Manage 2009; 38: 587–96. MEDLINE
e39. Ng AV: The underrecognized role of impaired muscle function in cancer-related fatigue. J Support Oncol 2010; 8: 177–8. MEDLINE
e40. Given B, Given CW, Sikorskii A, et al.: Establishing mild, moderate, and severe scores for cancer-related symptoms: how consistent and clinically meaningful are interference-based severity cut-points? J Pain Symptom Manage 2008; 35: 126–35. MEDLINE
e41. Andrykowski MA, Donovan KA, Laronga C, Jacobsen PB: Prevalence, predictors, and characteristics of off-treatment fatigue in breast cancer survivors. Cancer 2010; 116: 5740–8. CrossRef MEDLINE
e42. Murphy H, Alexander S, Stone P: Investigation of diagnostic criteria for cancer-related fatigue syndrome in patients with advanced cancer: a feasibility study. Palliat Med 2006; 20: 413–8. CrossRef MEDLINE
e43. Rudolf S, Bermejo I, Schweiger U, Hohagen F, Härter M: Diagnostik depressiver Störungen. Dtsch Arztebl 2006; 103: A 1754–62. VOLLTEXT
e44. Escalante CP, Kallen MA, Valdres RU, Morrow PK, Manzullo EF: Outcomes of a cancer-related fatigue clinic in a comprehensive cancer center. J Pain Symptom Manage 2010; 39: 691–701. MEDLINE
e45. Kuhnt S, Brähler E: Tumorassoziierte Fatigue. Psychother Psychosom Med Psychol 2010; 60: 402–8. CrossRef MEDLINE
e46. Glaus A, Frei IA, Knipping C, Ream E, Browne N: Attitude of cancer patients to fatigue: patient attitude in Switzerland and England. Pflege 2002; 15: 187–94. MEDLINE
e47.Gielissen MF, Verhagen S, Witjes F, Bleijenberg G: Effects of cognitive behavior therapy in severely fatigued disease-free cancer patients compared with patients waiting for cognitive behavior therapy: a randomized controlled trial. J Clin Oncol 2006; 24: 4882–7. CrossRef MEDLINE
e48. Barsevick AM, Dudley W, Beck S, Sweeney C, Whitmer K, Nail L:
A randomized clinical trial of energy conservation for patients with cancer-related fatigue. Cancer 2004; 100: 1302–10. CrossRef MEDLINE
e49. Yuen HK, Mitcham M, Morgan L: Managing post-therapy fatigue for cancer survivors using energy conservation training. J Allied Health 2006; 35: 121E–39E. MEDLINE
e50. Schmitz KH, Courneya KS, Matthews C, et al.: American college of sports medicine roundtable on exercise guidelines for cancer
survivors. Med Sci Sports Exerc 2010; 42: 1409–26. MEDLINE
e51.Blaney J, Lowe-Strong A, Rankin J, Campbell A, Allen J, Gracey J: The cancer rehabilitation Journey: Barriers to and facilitators of exercise among patients with cancer-related fatigue. Phys Ther 2010; 90: 1135–47. MEDLINE
e52.Minton O, Stone P, Richardson A, Sharpe M, Hotopf M: Drug therapy for the management of cancer related fatigue. Cochrane
Database Syst Rev 2010; 7 (CD006704). MEDLINE
e53. Eton DT, Cella D: Do erythropoietic-stimulating agents relieve fatigue? A review of reviews. Cancer Treat Res 2011; 157: 181–94. MEDLINE
e54. Dimeo F, Schmittel A, Fietz T, et al.: Physical performance, depression, immune status and fatigue in patients with hematological malignancies after treatment. Ann Oncol 2004; 15: 1237–42. MEDLINE
e55. Geinitz H, Zimmermann FB, Stoll P, et al.: Fatigue, serum cytokine levels, and blood cell counts during radiotherapy of patients with breast cancer. Int J Radiat Oncol Biol Phys 2001; 51: 691–8. MEDLINE
e56. Bohlius J, Schmidlin K, Brillant C, et al.: Recombinant human
erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials. Lancet 2009; 373: 1532–42. CrossRef MEDLINE
e57.Rizzo JD, Brouwers M, Hurley P, et al.: American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer. J Clin Oncol 2010; 28(33): 4996–5010. MEDLINE
e58. Roth AJ, Nelson C, Rosenfeld B, et al.: Methylphenidate for fatigue in ambulatory men with prostate cancer. Cancer 2010; 116: 5102–10. MEDLINE
e59. Lower EE, Fleishman S, Cooper A, et al.: Efficacy of dexmethyl-phenidate for the treatment of fatigue after cancer chemotherapy: a randomized clinical trial. J Pain Symptom Manage 2009; 38: 650–62. MEDLINE
e60. Yennurajalingam S, Palmer JL, Chacko R, Bruera E: Factors associated with response to methylphenidate in advanced cancer patients. Oncologist 2011; 16: 246–53. MEDLINE
e61. Jean-Pierre P, Morrow GR, Roscoe JA, et al.: A Phase 3 randomized, placebo-controlled, double-blind, clinical trial of the effect of Modafinil on cancer-related fatigue among 631 patients receiving chemotherapy. Cancer 2010; 15: 3513–20. MEDLINE
e62. Lundholm K, Gelin J, Hyltander A, et al.: Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors. Cancer Res 1994; 54: 5602–6. MEDLINE
e63.Kamath J, Feinn R, Winokur A: Thyrotropin-releasing hormone as a treatment for cancer-related fatigue: a randomized controlled study. Support Care Cancer 2011. MEDLINE
e64. Jia L, Zhao Y: Current evaluation of the millennium phytomedicine—ginseng (I): etymology, pharmacognosy, phytochemistry, market and regulations. Curr Med Chem 2009; 16: 2475–84. CrossRef MEDLINE PubMed Central
e65. Barton DL, Soori GS, Bauer BA, et al.: Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA. Support Care Cancer 2010; 18: 179–87. (Epub 2009 May 6). MEDLINE
e66. Younus J, Collins A, Wang X, et al.: A double blind placebo controlled pilot study to evaluate the effect of ginseng on fatigue and quality of life in adult chemo-naïve cancer patients. Proc Am Soc Clin Oncol 2003; 22: [abstr 2947].
e67. Fischer I, Boehm K, Horneber M, and CAM-Cancer Consortium. Ginseng [online document]. www.cam-cancer.org/CAM-Summaries/Biologically-Based-Practices/Ginseng. Last accessed on 12 July 2010.
e68. de Oliveira Campos MP, Riechelmann R, Martins LC, Hassan BJ, Casa FB, Giglio AD: Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy.
J Altern Complement Med 2011; 17: 505–12. CrossRef MEDLINE
e69. Hänsel R, Sticher O: Pharmakognosie Phytopharmazie. 8th edition. Heidelberg: Springer Medizin Verlag; 2007.
e70. Brown JC, Huedo-Medina TB, Pescatello LS, Pescatello SM, Ferrer RA, Johnson BT: Efficacy of Exercise interventions in modulating cancer-related fatigue among adult cancer survivors: A meta-analysis. Cancer Epidemiol Biomarkers Prev 2011; 20: 123–33. Epub 2010 Nov 4. MEDLINE
e71. Duijts SF, Faber MM, Oldenburg HS, van Beurden M, Aaronson NK: Effectiveness of behavioral techniques and physical exercise on psychosocial functioning and health-related quality of life in breast cancer patients and survivors—a meta-analysis. Psychooncology 2011; 20: 115–26. MEDLINE
e72. Velthuis MJ, Agasi-Idenburg SC, Aufdemkampe G, Wittink HM: The effect of physical exercise on cancer-related fatigue during cancer treatment: a meta-analysis of randomised controlled trials. Clin Oncol (R Coll Radiol) 2010; 22: 208–21. CrossRef MEDLINE
e73. Dimeo F, Schwartz S, Wesel N, Voigt A, Thiel E: Effects of an endurance and resistance exercise program on persistent cancer-related fatigue after treatment. Ann Oncol 2008; 19: 1495–9. CrossRef MEDLINE
e74. Dimeo FC, Stieglitz RD, Novelli-Fischer U, Fetscher S, Keul J: Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer 1999; 85: 2273–7. MEDLINE
e75. Goedendorp MM, Gielissen MF, Verhagen CA, Bleijenberg G: Psychosocial interventions for reducing fatigue during cancer treatment in adults. Cochrane Database Syst Rev 2009; CD006953. MEDLINE
e76.Kangas M, Bovbjerg DH, Montgomery GH: Cancer-related fatigue: a systematic and meta-analytic review of non-pharmacological therapies for cancer patients. Psychol Bull 2008; 134: 700–41. CrossRef MEDLINE
e77. van der Lee ML, Garssen B: Mindfulness-based cognitive therapy reduces chronic cancer-related fatigue: a treatment study. Psycho-oncology 2010 Dec 19 [Epub ahead of print]. MEDLINE
e78. Dimeo FC, Thomas F, Raabe-Menssen C, Propper F, Mathias M: Effect of aerobic exercise and relaxation training on fatigue and physical performance of cancer patients after surgery. A randomised controlled trial. Support Care Cancer 2004; 12: 774–9. CrossRef MEDLINE
e79. Carlson LE, Garland SN: Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients. Int J Behav Med 2005; 12: 278–85. CrossRef MEDLINE
e80. Dimeo FC: Bewegung im eigenen Takt – Körperliche Aktivität und Sport bei Tumorerkrankungen. Im Focus Onkologie 2010; 5: 60–6.
e81. Mortimer JE, Barsevick AM, Bennett CL, et al.: Studying cancer-related fatigue: Report of the NCCN Scientific Research Committee. J Natl Compr Canc Netw 2010; 8: 1331–9. MEDLINE