1. | Umwelt Bundesamt: Feinstaub. www.umweltbundesamt.de/themen/luft/luftschadstoffe/feinstaub (last accessed on 15 June 2019). |
2. | Sutton MA, Howard CM, Erisman JW, et al.: The European nitrogen assessment. Sources, effects and policy perspectives. United Kingdom: Cambridge University Press 2011. |
3. | Cassee FR, Héroux ME, Gerlofs-Nijland ME, Kelly FJ: Particulate matter beyond mass: recent health evidence on the role of fractions, chemical constituents and sources of emission. Inhal Toxicol 2013; 25: 802–12 CrossRef MEDLINE PubMed Central |
4. | Pope CA 3rd, Muhlestein JB, May HT, Renlund DG, Anderson JL, Horne BD: Ischemic heart disease events triggered by short-term exposure to fine particulate air pollution. Circulation 2006; 114: 2443–8 CrossRef MEDLINE |
5. | Prussin AJ 2nd, Marr LC: Sources of airborne microorganisms in the built environment. Microbiome 2015; 3: 78 CrossRef MEDLINE PubMed Central |
6. | Halliwell B, Hu ML, Louie S, et al.: Interaction of nitrogen dioxide with human plasma. Antioxidant depletion and oxidative damage. FEBS Lett 1992; 313: 62–6 CrossRef |
7. | Eidgenössische Kommission für Lufthygiene: Stickstoffhaltige Luftschadstoffe in der Schweiz. Status-Bericht der Eidgenössische Kommission für Lufthygiene. Bern: Bundesamt für Umwelt, Wald und Landschaft BUWAL 2005. |
8. | Umwelt Bundesamt: Luftschadstoffbelastung in Deutschland. http://gis.uba.de/Website/luft/index.html (last accessed on 15 June 2019). |
9. | Umwelt Bundesamt: Stickstoffoxide. www.umweltbundesamt.de/themen/luft/luftschadstoffe/stickstoffoxide (last accessed on 15 June 2019). |
10. | Turner MC, Jerrett M, Pope CA , et al.: Long-term ozone exposure and mortality in a large prospective study. Am J Respir Crit Care Med 2016; 193: 1134–42 CrossRef MEDLINE PubMed Central |
11. | Brown JS: Nitrogen dioxide exposure and airway responsiveness in individuals with asthma. Inhal Toxicol 2015; 27: 1–14 CrossRef MEDLINE |
12. | Brunekreef B, Beelen R, Hoek G, et al.: Effects of long-term exposure to traffic-related air pollution on respiratory and cardiovascular mortality in the Netherlands: The NLCS-AIR Study. Res Rep Health Eff Inst, Boston, MA 2019; 5–71. |
13. | Atkinson RW, Butland BK, Anderson HR, Maynard RL: Long-term concentrations of nitrogen dioxide and mortality: A meta-analysis of cohort studies. Epidemiology 2018; 29: 460–72 CrossRef MEDLINE PubMed Central |
14. | Schneider A, Cyrys J, Breitner S, Kraus U, Peters A: Quanitifizierung von umweltbedingten Krankheitslasten aufgrund der Stickstoffdioxid-Exposition in Deutschland. Neuherberg: Umwelt & Gesundheit 2018. |
15. | Karoui A, Crochemore C, Mulder P, et al.: An integrated functional and transcriptomic analysis reveals that repeated exposure to diesel exhaust induces sustained mitochondrial and cardiac dysfunctions. Environ Pollut 2019; 246: 518–26 CrossRef MEDLINE |
16. | Thurston GD: A critical review of PM10-mortality time-series studies. J Expo Anal Environ Epidemiol 1996; 6: 3–21. |
17. | Helmholtz Zentrum München: Kooperative Gesundheitsforschung in der Region Augsburg (KORA). www.helmholtz-muenchen.de/kora/index.html (last accessed on 15 June 2019). |
18. | Eeftens M, Beelen R, de Hoogh K, et al.: Development of land use regression models for PM2.5, PM2.5 absorbance, PM10 and PMcoarse in 20 European study areas; results of the ESCAPE project. Environ Sci Technol 2012; 46: 11195–205 CrossRef MEDLINE |
19. | Mahabadi AA, Möhlenkamp S, Moebus S, et al.: The Heinz Nixdorf Recall study and its potential impact on the adoption of atherosclerosis imaging in European primary prevention guidelines. Curr Atheroscler Rep 2011; 13: 367–72 CrossRef MEDLINE |
20. | American Cancer Society: Cancer Prevention Study II (CPS II). www.cancer.org/research/we-conduct-cancer-research/epidemiology/cancer-prevention-study-2.html (last accessed on 15 June 2019). |
21. | World Health Organization: WHO guidelines for indoor air quality: selected pollutants. Copenhagen: World Health Organization Regional Office for Europe 2010. |
22. | Umwelt Bundesamt: Innenraumluft. www.umweltbundesamt.de/themen/gesundheit/umwelteinfluesse-auf-den-menschen/innenraumluft (last accessed on 29 September 2019). |
23. | Campen M, Robertson S, Lund A, Lucero J, McDonald J: Engine exhaust particulate and gas phase contributions to vascular toxicity. Inhal Toxicol 2014; 26: 353–60 CrossRef MEDLINE PubMed Central |
24. | World Health Organization: Review of evidence on health aspects of air pollution – REVIHAAP Project: Technical Report. Copenhagen: WHO Regional Office for Europe 2013. |
25. | Cesaroni G, Forastiere F, Stafoggia M, et al.: Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project. BMJ 2014; 348: f7412. |
26. | Friedman MS, Powell KE, Hutwagner L, Graham LM, Teague WG: Impact of changes in transportation and commuting behaviors during the 1996 Summer Olympic Games in Atlanta on air quality and childhood asthma. JAMA 2001; 285: 897–905 CrossRef MEDLINE |
27. | Lin WW, Huang W, Zhu T, et al.: Acute respiratory inflammation in children and black carbon in ambient air before and during the 2008 Beijing olympics. Environ Health Perspect 2011; 119: 1507–12 CrossRef MEDLINE PubMed Central |
28. | Pope CA 3rd: Respiratory disease associated with community air pollution and a steel mill, Utah Valley. Am J Public Health 1989; 79: 623–8 CrossRef MEDLINE PubMed Central |
29. | Casey JA, Karasek D, Ogburn EL, et al. : Retirements of coal and oil power plants in California: association with reduced preterm birth among populations nearby. Am J Epidemiol 2018; 187: 1586–94 CrossRef MEDLINE PubMed Central |
30. | Gauderman WJ, Avol E, Gilliland F, et al.: The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med 2004; 351: 1057–67 CrossRef MEDLINE |
31. | Thurston GD, Kipen H, Annesi-Maesano I, et al.: A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur Respir J 2017; 49 CrossRef MEDLINE PubMed Central |
32. | Sun Z, Zhu D: Exposure to outdoor air pollution and its human health outcomes: A scoping review. PLoS One 2019; 14: e0216550 CrossRef MEDLINE PubMed Central |
33. | Beelen R, Raaschou-Nielsen O, Stafoggia M, et al.: Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project. Lancet 2014; 383: 785–95 CrossRef |
34. | Hoek G, Krishnan RM, Beelen R, et al. : Long-term air pollution exposure and cardio-respiratory mortality: a review. Environ Health 2013; 12: 43 CrossRef MEDLINE PubMed Central |
35. | Kutlar JM, Eeftens M, Gintowt E, Kappeler R, Künzli N: Time to harmonize national ambient air quality standards. Int J Public Health 2017; 62: 453–62 CrossRef MEDLINE PubMed Central |
36. | Pope CA 3rd, Ezzati M, Dockery DW: Fine-particulate air pollution and life expectancy in the United States. N Engl J Med 2009; 360: 376–86 CrossRef MEDLINE PubMed Central |
37. | Brønnum-Hansen H, Bender AM, Andersen ZJ, et al.: Assessment of impact of traffic-related air pollution on morbidity and mortality in Copenhagen municipality and the health gain of reduced exposure. Environ Int 2018; 121: 973–80 CrossRef MEDLINE |
38. | Castro A, Künzli N, Götschi T: Health benefits of a reduction of PM10 and NO2 exposure after implementing a clean air plan in the Agglomeration Lausanne-Morges. Int J Hyg Environ Health 2017; 220: 829–39 CrossRef MEDLINE |
e1. | Peters A, Hoffmann B, Brunekreef B, et al.: Die Rolle der Luftschadstoffe für die Gesundheit. Eine Expertise im Namen der Internationalen Gesellschaft für Umweltepidemiologie (ISEE) und der European Respiratory Society (ERS) 2019. https://ers.app.box.com/s/lab57dxgqqzmbbzjhempf5oiob8s795b (last accessed on 29 September 2019). |
e2. | U.S. Environmental Protection Agency: Integrated Science Assessment (ISA) for particulate matter (Final Report, Dec 2009). Washington, DC: U.S. Environmental Protection Agency 2009. |
e3. | McConnell R, Berhane K, Gilliland F, et al.: Prospective study of air pollution and bronchitic symptoms in children with asthma. Am J Respir Crit Care Med 2003; 168: 790–797 CrossRef MEDLINE |
e4. | Peters A, Liu E, Verrier RL, et al.: Air pollution and incidence of cardiac arrhythmia. Epidemiology 2000; 11: 11–17 CrossRef MEDLINE |
e5. | International Agency for Research on Cancer: Outdoor air pollution/IARC monographs on the evaluation of carcinogenic risks to humans. Lyon: International Agency for Research on Cancer 2016. |
e6. | Turner MC, Krewski D, Diver WR, et al: Ambient air pollution and cancer mortality in the cancer prevention study II. Environ Health Perspect 2017; 125: 087013 CrossRef MEDLINE PubMed Central |
e7. | Cesaroni G, Badaloni C, Gariazzo C, et al.: Long-term exposure to urban air pollution and mortality in a cohort of more than a million adults in Rome. Environ Health Perspect 2013; 121: 324–31 CrossRef MEDLINE PubMed Central |
e8. | Carey IM, Atkinson RW, Kent AJ, van Staa T, Cook DG, Anderson HR: Mortality associations with long-term exposure to outdoor air pollution in a national English cohort. Am J Respir Crit Care Med 2013; 187: 1226–33 CrossRef MEDLINE PubMed Central |
e9. | U.S. Environmental Protection Agency: Integrated Science Assessment (ISA) of ozone and related photochemical oxidants (Final Report, Feb 2013). Washington, DC: U.S. Environmental Protection Agency 2013. |
e10. | U.S. Environmental Protection Agency: Integrated Science Assessment for oxides of nitrogen – Health criteria. Research Triangle Park: Office of Research and Development, National Center for Environmental Assessment 2016. |
e11. | Hill AB: The environment and disease: association or causation? Proc R Soc Med 1965; 58: 295–300 CrossRef |
e12. | WHO, International Agency for Research on Cancer: IARC monographs on the identification of carcinogenic hazards to humans.; Lyon France. Amended 2019 (last accessed on 29 September 2019). |
e13. | Owens EO, Patel MM, Kirrane E, et al.: Framework for assessing causality of air pollution-related health effects for reviews of the National Ambient Air Quality Standards. Regul Toxicol Pharmacol 2017; 88: 332–7 CrossRef MEDLINE PubMed Central |
e14. | Li Y, Wang W, Kan H, Xu X, Chen B: Air quality and outpatient visits for asthma in adults during the 2008 Summer Olympic Games in Beijing. Sci Total Environ 2010; 408: 1226–7 CrossRef MEDLINE |
e15. | Zhang Z, Wang J, Liu F, et al.: Impacts of event-specific air quality improvements on total hospital admissions and reduced systemic inflammation in COPD patients. PLoS One 2019; 14: e0208687 CrossRef MEDLINE PubMed Central |
e16. | Avol EL, Gaudermann WJ, Tan SM, London SJ, Peters JM: Respiratory effects of relocating to areas of differing air pollution levels. AM J Respir VCrit Care Med 2001; 164: 2067–72 CrossRef MEDLINE |
e17. | Martin AE, Bradley WH: Mortality, fog and atmospheric pollution: an investigation during the winter of 1958–59. Mon Bull Minist Health Public Health Lab Serv 1960; 19: 56–72. |
e18. | Hechter HH, Goldsmith JR: Air pollution and daily mortality. Am J Med Sci 1961;241: 581–8 CrossRef |
e19. | Rumford J : Mortality studies in relation to air pollution. Am J Public Health Nations Health 1961; 51: 165–73 CrossRef MEDLINE PubMed Central |
e20. | Schwartz J, Dockery DW: Increased mortality in Philadelphia associated with daily air pollution concentrations. Am Rev Respir Dis 1992; 145: 600–4 CrossRef MEDLINE |
e21. | Stocks P, Campbell JM: Lung cancer death rates among non-smokers and pipe and cigarette smokers: An evaluation in relation to air pollution by benzpyrene and other substances. BMJ 1955; 2: 923–9 CrossRef MEDLINE PubMed Central |
e22. | He D, Wu S, Zhao H, et al.: Association between particulate matter 2.5 and diabetes mellitus: a meta-analysis of cohort studies. J Diabetes Investig 2017; 8: 687–96 CrossRef MEDLINE PubMed Central |
e23. | Pedersen M, Stayner L, Slama R, et al.: Ambient air pollution and pregnancy-induced hypertensive disorders: a systematic review and meta-analysis. Hypertension 2014; 64: 494–500 CrossRef MEDLINE |
e24. | Sun X, Luo X, Zhao C, et al.: The associations between birth weight and exposure to fine particulate matter (PM2.5) and its chemical constituents during pregnancy: a meta-analysis. Environ Pollut 2016; 211:38–47 CrossRef MEDLINE |
e25. | Schultz ES, Litonjua AA, Melen E: Effects of long-term exposure to traffic-related air pollution on lung function in children. Curr Allergy Asthma Rep 2017; 17: 41 CrossRef MEDLINE PubMed Central |
e26. | Clifford A, Lang L, Chen R, Anstey KJ, Seaton A: Exposure to air pollution and cognitive functioning across the life course— a systematic literature review. Environ Res 2016; 147: 383–98 CrossRef MEDLINE |
e27. | Ngoc LTN, Park D, Lee Y, Lee YC: Systematic Review and Meta-analysis of human skin diseases due to particulate matter. Int J Environ Res Public Health 2017; 14: E1458 CrossRef MEDLINE PubMed Central |
e28. | Ljungman PL, Mittleman MA: Ambient air pollution and stroke. Stroke 2014; 45: 3734–41 CrossRef MEDLINE PubMed Central |
e29. | Ritz B, Lee PC, Hansen J, et al.: Traffic-related air pollution and Parkinson’s disease in Denmark: A case–control study. Environ Health Perspec 2016; 124: 351–6 CrossRef MEDLINE PubMed Central |
e30. | Paul KC, Haan M, Mayeda ER, Ritz BR: Ambient air pollution, noise, and late-life cognitive decline and dementia risk. Annu Rev Public Health 2019; 40: 203–20 CrossRef MEDLINE PubMed Central |
e31. | Power MC, Adar SD, Yanosky JD, Weuve J: Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: a systematic review of epidemiologic research. Neurotoxicology 2016; 56: 235–53 CrossRef MEDLINE PubMed Central |
e32. | Plass D, Vos T, Hornberg C, Scheidt-Nave C, Zeeb H, Krämer A: Trends in disease burden in Germany—results, implications and limitations of the Global Burden of Disease Study. Dtsch Arztebl Int 2014; 111: 629–38 VOLLTEXT |
e33. | World Health Organization: Health risks of air pollution in Europe – HRAPIE project. Copenhagen: World Health Organization Regional Office for Europe 2013. |
e34. | Di Q, Wang Y, Zanobetti A, et al.: Air pollution and mortality in the medicare population. N Engl J Med 2017; 376: 2513–22 CrossRef MEDLINE PubMed Central |
e35. | Strak M, Weinmayr G, Rodopolou S, et al: Natural and cause-specific mortality and low-level air pollution in a pooled cohort of 392,826 participants in Europe: the ELAPSE project. https://journals.lww.com/environepidem/toc/2019/10001 (last accessed on 12 March 2019). |
e36. | Eidgenössische Kommission for Lufthygiene: Feinstaub in der Schweiz 2013. Bern: Eidgenössische Kommission for Lufthygiene 2013. |
e37. | Der Schweizerische Bundesrat: Luftreinhalte-Verordnung (LRV) vom 16. Dezember 1985 (Stand am 16. April 2018). Bern: Der Schweizerische Bundesrat 1985. |
e38. | Amann M, Holland M, Maas R, Saveyn B, Vandyck T: Costs, benefits and economic impacts of the EU clean air strategy and their implications on innovation and competitiveness. Laxxenburg: International Institute for Applied Systems Analysis (IIASA) 2017. |
e39. | U.S. Environmental Protection Agency: Economic and cost analysis for air pollution regulations. www.epa.gov/economic-and-cost-analysis-air-pollution-regulations (last accessed on 15 June 2019). |