DÄ internationalArchiveReferences

Review article

In Vitro Fertilization Technology and Child Health

Dtsch Arztebl Int 2020; 117: 23-30. DOI: 10.3238/arztebl.2020.0023

von Wolff, M; Haaf, T

1.Scherrer U, Rimoldi SF, Rexhaj E, et al.: Systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies. Circulation 2012; 125: 1890–6 CrossRef MEDLINE
2.Meister TA, Rimoldi SF, Soria R, et al.: Association of assisted reproductive technologies with arterial hypertension during adolescence. J Am Coll Cardiol 2018; 72: 1267–74 CrossRef MEDLINE
3.Qin J, Sheng X, Wang H, Liang D, Tan H, Xia J: Assisted reproductive technology and risk of congenital malformations: a meta-analysis based on cohort studies. Arch Gynecol Obstet 2015; 292: 777–98 CrossRef MEDLINE
4.Zheng Z, Chen L, Yang T, Yu H, Wang H, Qin J: Multiple pregnancies achieved with IVF/ICSI and risk of specific congenital malformations: a meta-analysis of cohort studies. Reprod Biomed Online 2018; 36: 472–82 CrossRef MEDLINE
5.Hoorsan H, Mirmiran P, Chaichian S, Moradi Y, Hoorsan R, Jesmi F: Congenital malformations in infants of mothers undergoing assisted reproductive technologies: a systematic review and meta-analysis study. J Prev Med Public Health 2017; 50: 347–60 CrossRef MEDLINE PubMed Central
6.Giorgione V, Parazzini F, Fesslova V, et al.: Congenital heart defects in IVF/ICSI pregnancy: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2018; 51: 33–42 CrossRef MEDLINE
7.Qin JB, Sheng XQ, Wu D, et al.: Worldwide prevalence of adverse pregnancy outcomes among singleton pregnancies after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis. Arch Gynecol Obstet 2017; 295: 285–301 CrossRef CrossRef
8.Qin J, Wang H, Sheng X, Liang D, Tan H, Xia J: Pregnancy-related complications and adverse pregnancy outcomes in multiple pregnancies resulting from assisted reproductive technology: a meta-analysis of cohort studies. Fertil Steril 2015; 103: 1492–508.e1–7 CrossRef MEDLINE
9.Maheshwari A, Pandey S, Amalraj Raja E, Shetty A, Hamilton M, Bhattacharya S: Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer? Hum Reprod Update 2018; 24: 35–58 CrossRef MEDLINE
10.Massaro PA, MacLellan DL, Anderson PA, Romao RL: Does intracytoplasmic sperm injection pose an increased risk of genitourinary congenital malformations in offspring compared to in vitro fertilization? A systematic review and meta-analysis. J Urol 2015; 193 (5 Suppl): 1837–42 CrossRef MEDLINE
11.Guo XY, Liu XM, Jin L, et al.: Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis. Fertil Steril 2017; 107: 622–31 CrossRef MEDLINE
12.Schweizerische Eidgenossenschaft: Geburten. www.bfs.admin.ch/bfs/de/home/statistiken/bevoelkerung/geburten-todesfaelle/geburten.html (last accessed on 8 September 2019).
13.Davies MJ, Moore VM, Willson KJ, et al.: Reproductive technologies and the risk of birth defects. N Engl J Med 2012; 366: 1803–13 CrossRef MEDLINE
14.Rumbold AR, Moore VM, Whitrow MJ, et al.: The impact of specific fertility treatments on cognitive development in childhood and adolescence: a systematic review. Hum Reprod 2017; 32: 1489–507 CrossRef MEDLINE
15.Catford SR, McLachlan RI, O‘Bryan MK, Halliday JL: Long-term follow-up of intra-cytoplasmic sperm injection-conceived offspring compared with in vitro fertilization-conceived offspring: a systematic review of health outcomes beyond the neonatal period. Andrology 2017; 5: 610–21 CrossRef MEDLINE
16.Lazaraviciute G, Kauser M, Bhattacharya S, et al.: A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF/ICSI compared with children conceived spontaneously. Hum Reprod Update 2014; 20: 840–52 CrossRef MEDLINE
17.Mussa A, Molinatto C, Cerrato F, et al.: Assisted reproductive techniques and risk of Beckwith-Wiedemann syndrome. Pediatrics 2017; 140: e20164311 CrossRef MEDLINE
18.Hiura H, Okae H, Miyauchi N, et al.: Characterization of DNA methylation errors in patients with imprinting disorders conceived by assisted reproduction technologies. Hum Reprod 2012; 27: 2541–8 CrossRef MEDLINE
19.El Hajj N, Haaf T: Epigenetic disturbances in in vitro cultured gametes and embryos: implications for human assisted reproduction. Fertil Steril 2013; 99: 632–41 CrossRef MEDLINE
20.Santi D, De Vincentis S, Magnani E, Spaggiari G: Impairment of sperm DNA methylation in male infertility: a meta-analytic study. Andrology 2017; 5: 695–703 CrossRef MEDLINE
21.Nelissen EC, Dumoulin JC, Daunay A, Evers JL, Tost J, van Montfoort AP: Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions. Hum Repro 2013; 28: 1117–26 CrossRef MEDLINE
22.Fauque P: Ovulation induction and epigenetic anomalies. Fertil Steril 2013; 99: 616–23 CrossRef MEDLINE
23.Choufani S, Turinsky AL, Melamed N, et al.: Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome. Hum Mol Genet 2019; 28: 372–85 CrossRef MEDLINE
24.Oldereid NB, Wennerholm UB, Pinborg A, et al.: The effect of paternal factors on perinatal and paediatric outcomes: a systematic review and meta-analysis. Hum Reprod Update 2018; 24: 320–89 CrossRef MEDLINE
25.Pinborg A, Wennerholm UB, Romundstad LB, et al.: Why do singletons conceived after assisted reproduction technology have adverse perinatal outcome? Systematic review and meta-analysis. Hum Reprod Update 2013; 19: 87–104 CrossRef MEDLINE
26.Luke B, Gopal D, Cabral H, Stern JE, Diop H: Pregnancy, birth, and infant outcomes by maternal fertility status: the Massachusetts Outcomes Study of Assisted Reproductive Technology. Am J Obstet Gynecol 2017; 217: 327. e1–327.e14 CrossRef MEDLINE PubMed Central
27.Henningsen AA, Gissler M, Skjaerven R, et al.: Trends in perinatal health after assisted reproduction: a Nordic study from the CoNARTaS group. Hum Reprod 2015; 30: 710–6 CrossRef MEDLINE
28.Barker DJ, Osmond C, Golding J, Kuh K, Wadsworth ME: Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989; 298: 564–7 CrossRef MEDLINE PubMed Central
29.Roseboom T, de Rooij S, Painter R: The Dutch famine and its long-term consequences for adult health. Early Hum Dev 2006; 82: 485–91 CrossRef MEDLINE
30.McMillen IC, MacLaughlin SM, Muhlhausler BS, Gentili S, Duffield JL, Morrison JL: Developmental origins of adult health and disease: the role of periconceptional and foetal nutrition. Basic Clin Pharmacol Toxicol 2008; 102: 82–9 CrossRef
31.Lehnen H, Zechner U, Haaf T: Epigenetics of gestational diabetes mellitus and offspring health: the time for action is in early stages of life. Mol Hum Reprod 2013; 19: 415–22 CrossRef MEDLINE PubMed Central
32.Gluckman PD, Hanson MA, Buklijas T, Low FM, Beedle AS: Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol 2009; 5: 401–8 CrossRef MEDLINE
33.El Hajj N, Schneider E, Lehnen H, Haaf T: Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment. Reproduction 2014; 148: R111–20 CrossRef MEDLINE PubMed Central
34.Lillycrop KA, Slater-Jefferies JL, Hanson MA, Godfrey KM, Jackson AA, Burdge GC: Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications. Br J Nutr 2007; 97: 1064–73 CrossRef MEDLINE PubMed Central
35.Waterland RA, Travisano M, Tahiliani KG, Rached MT, Mirza S: Methyl donor supplementation prevents transgenerational amplification of obesity. Int J Obes (Lond) 2008; 32: 1373–9 CrossRef MEDLINE PubMed Central
36.Khulan B, Cooper WN, Skinner BM, et al.: Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in the Gambia. Hum Mol Genet 2012; 21: 2086–101 CrossRef MEDLINE
37.Hiura H, Okae H, Chiba H, et al.: Imprinting methylation errors in ART. Reprod Med Biol 2014; 13: 193–202 CrossRef MEDLINE PubMed Central
38.Estill MS, Bolnick JM, Waterland RA, Bolnick AD, Diamond MP, Krawetz SA: Assisted reproductive technology alters deoxyribonucleic acid methylation profiles in bloodspots of newborn infants. Fertil Steril 2016; 106: 629–39 CrossRef MEDLINE
39.El Hajj N, Haertle L, Dittrich M, et al.: DNA methylation signatures in cord blood of ICSI children. Hum Reprod 2017; 32: 1761–9 CrossRef MEDLINE PubMed Central
40.Ungewitter E, Scrable H: Antagonistic pleiotropy and p53. Mech Ageing Dev 2009; 130: 10–7 CrossRef MEDLINE PubMed Central